In the Mirror of Patenting: A Glimpse of the 2017 Drug Repurposing Theatre

Along the lines that have been discussed in a recent Frontiers short paper, here is a list of our patent discussions in the December 2017 drug repurposing special issue of ASSAY and Drug Development Technologies:

WO/2017/059389 (Kythera Biopharmaceuticals, USA): Statins as an alternative to liposuction and cryolipolysis

WO/2017/060308 (AB Science, France): Masitinib switches to human use

WO/2017/066421 (Ovid Therapeutics, USA): Eplivanserin for improving cognition in psychoses

WO/2017/068143 (Individual, Germany): BAY 11-7082 or dimethyl fumarate for adiposity or cardiovascular diseases

WO/2017/080919 (Freiburg University, Germany): Roflumilast for metabolic lipid disorders

WO/2017/081609 (Individuals): Febuxostat: from gout to neurology

WO/2017/085407 (Pierre et Marie Curie University et al., France): Mirabegron, an overactive bladder drug, for macular degeneration

WO/2017/091644 (AZ Therapies, USA): Cromolyn for cerebral ischemia and dementia

WO/2017/096013 (Cornell University, USA): Deferiprone for COPD

WO/2017/097311 (Aarhus University, Denmark): Rufinamide improves delayed muscle reaxation

WO/2017/104833 ( Link Genomics & Rohto Pharmaceutical, Japan): Many potential alternatives for atrophic age-related macular degeneration

WO/2017/108441 (Maastricht University, The Netherlands): Riociguat, a pulmonary hypertension drug, improves impaired cognition

WO/2017/118857 ( Chronos Therapeutics, UK): Tacrolimus for amyotrophic lateral sclerosis and frontotemporal dementias

WO/2017/123744 (Grace Therapeutics, USA): Betamethasone oral spray for ataxia-telangiectasia

WO/2017/125502 (Bordeaux University et al.): Antiplatelet agents for systemic sclerosis

WO/2017/129577 (Sooft Italia): Gabapentin eyedrops support healing of corneal ulcers

WO/2017/131576 (Ultupharma, Sweden): zidovudine/uridine/trimethoprim combo for bacterial infections

WO/2017/137576 (Zürich University): Dimethyl fumarate for gout, acne, diabetes, vitiligo and/or pyoderma gangrenosum

WO/2017/140828 (INSERM & CNRS, France): Alpelisib for PROS-CLOVES syndrome

WO/2017/143964 (Institut Pasteur of Shanghai, China): Quisinostat, an oncology drug candidate, repurposed for malaria

WO/2017/155053 (Wakayama Medical University, Japan): Lansoprazole – from heartburn to hepatic degeneration

WO/2017/158356 (University of Newcastle upon Tyne, UK): Carbamazepine stimulates intracellular degradation of mutant collagens in chondrodysplasias

WO/2017/165508 (IM Therapeutics & Colorado University, USA): Methyldopa for Type 1 diabetes